A Mouse Model of Postoperative Pain

A Mouse Model of Postoperative Pain

Blog Article

Postoperative pain is cartoon martian with big head highly debilitating and hinders recovery.Opioids are the main pain medication used for acute postoperative pain.Given the devastating opioid addiction and overdose epidemic across the US, non-opioid pain therapeutics are desperately needed.In order to develop novel, non-opioid therapies for the treatment of postoperative pain and identify the mechanisms underlying this pain, rodent models of incisional pain have been established.The protocol herein describes in detail how to create a mouse model of postoperative pain that was adapted from established protocols.

This model here of postoperative pain is frequently-used, highly reproducible, and results in peripheral and central nervous system alterations.